CAS NO: | 651-06-9 |
包装: | 50mg |
规格: | 98% |
市场价: | 391元 |
分子量: | 280.3 |
Background:
Sulfameter(Bayrena) is a long-acting sulfonamide antibacterial.Target: AntibacterialSulfameter(Bayrena) is a long-acting sulfonamide antibacterial. It is used as a leprostatic agent in the treatment of urinary tract infections.Six physically healthy patients each were given 2 g of sulfameter simultaneously with a high lipid, high protein and high carbohydrate test meal. This experiment was designed as a threefold crossover study, and there was a randomized assignment of patients to the different conditions. The results show that sulfameter is significantly better absorbed when administered with a high lipid meal than when given with a high protein or high carbohydrate meal, demonstrated by the areas under the serum concentration curves (AUC), by the peak serum concentration and by the cumulative renal excretion.
参考文献:
[1]. Kaumeier S. The effect of the composition of food on the absorption of sulfameter. Int J Clin Pharmacol Biopharm. 1979 Jun;17(6):260-3.
[2]. Robins AH. Sulfameter (Sulla). Clin Pharmacol Ther. 1969 Jul-Aug;10(4):591-4.