CAS NO: | 1809249-37-3 |
规格: | 98% |
分子量: | 602.58 |
包装 | 价格(元) |
5mg | 电议 |
25mg | 电议 |
100mg | 电议 |
500mg | 电议 |
瑞德西韦 Remdesivir(GS-5734)
瑞德西韦,英文名字:Remdesivir,别名:GS-5734,CAS:1809249-37-3是一种核苷类似物,具有一定的抗冠状病毒(Coronaviruses)活性,在 HAE 细胞中,对 SARS-CoV 和 MERS-CoV 的 EC50 值为 74 nM,在延迟脑肿瘤细胞中,对鼠肝炎病毒的 EC50 值为 30 nM。Remdesivir 有潜力用于 2019-nCoV (COVID-19) 研究。
CAS:1809249-37-3
分子式:C27H35N6O8P
分子量:602.58
纯度:98%
存储:Store at -20°C
库存:现货
Background:
Remdesivir is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.
Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h[1].
References
[1]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.