AR-9281 是一种有效、选择性的可溶性环氧化物水解酶 (s-EH) 抑制剂,有治疗高血压和 2 型糖尿病的潜力。
CAS:913548-29-5
分子式:C18H29N3O2
分子量:319.44
纯度:98%
存储:Store at -20°C
Background:
AR9281 is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH), with potential for the treatment of hypertension and type 2 diabetes[1].
s-EH[1]
[1]. Chen D, et al. Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects. J Clin Pharmacol. 2012 Mar;52(3):319-28.