IDO-IN-3是一种有效的吲哚胺-2,3-双加氧酶(IDO)抑制剂,IC50为290nM。
CAS:2070018-30-1
分子式:C11H12BrFN6O2
分子量:359.15
纯度:98%
存储:Store at -20°C
Background:
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.
IDO-IN-3 (Compound 4c) is a potent (HeLa IC50=98 nM) inhibitor of IDO[1].
[1]. Yue EW, et al. INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology. ACS Med Chem Lett. 2017 Mar 6;8(5):486-491.