CAS NO: | 490-91-5 |
规格: | 98% |
分子量: | 164.2 |
包装 | 价格(元) |
5g | 电议 |
25g | 电议 |
Background:
The black seeds of Nigella have long been ingested to treat a broad range of diseases, including inflammation and cancer.1 Thymoquinone is a natural phytochemical isolated from the seeds of N. sativa.1 It has anti-inflammatory effects, blocking the synthesis of leukotrienes.2,1 Thymoquinone inhibits the growth of leukemia cells (IC50 = 1.5 μg/ml), inducing apoptosis by down-regulating the expression of Bcl-2 while up-regulating Bax expression.3 In addition to blocking cell proliferation and triggering apoptosis, thymoquinone (15 μM) suppresses STAT3-regulated gene expression and prevents angiogenesis.4,5