renal outer medullary potassium channel (Kir1.1, ROMK) antagonist
CAS:1315380-70-1
分子式:C16H12N6O5.HCl
分子量:404.76
纯度:98%
存储:Store at -20°C
Background:
VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM[1].
参考文献:
[1]. Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79(1):42-50.