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Irbesartan
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Irbesartan图片
CAS NO:138402-11-6
规格:98%
分子量:428.53
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Angiotensin II inhibitor
CAS:138402-11-6
分子式:C25H28N6O
分子量:428.53
纯度:98%
存储:Store at -20°C

Background:

Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.Target: Angiotensin ReceptorIrbesartan treatment markedly induces the expression of the adipogenic marker gene adipose protein 2 (aP2) in 3T3-L1 cells in a concentration-dependent manner with EC50 of 3.5 μM and 3.3-fold induction at the concentration of 10 μM. Irbesartan (10 μM) markedly induces transcriptional activity of the peroxisome proliferator–activated receptor-γ (PPARγ) by 3.4-fold independent of its AT1 receptor blocking action. Pretreatment with Irbesartan (