Ledipasvir acetone 是 Ledipasvir 的活性药物成分。Ledipasvir 是 hepatitis C virus NS5A 的有效抑制剂,能够抑制 GT1a 和 GT1b 复制子活性,EC50 值分别为 34 pM 和 4 pM。
CAS:1441674-54-9
分子式:C52H60F2N8O7
分子量:947.08
纯度:98%
存储:Store at -20°C
Background:
Ledipasvir acetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
Ledipasvir acetone is considered the active pharmaceutical ingredient, which is converted to Ledipasvir spray-dried dispersion, an amorphous free base.