GNF179是8,8-dimethyl IP类似物，具有良好的体外代谢稳定性和体内口服生物相容性。
CAS：1261114-01-5
分子式：C22H23ClFN5O
分子量：427.9
纯度：98%
存储：Store at -20°C

Background:

GNF179 is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.IC50 value: 4.8 nM [1]Target: Anti-parasitic agent GNF179 exhibits a low clearance (CL=22 ml/min/kg,