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Pocapavir(SCH-48973)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pocapavir(SCH-48973)图片
CAS NO:146949-21-5
规格:98%
分子量:423.72
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Pocapavir是一种肠病毒衣壳抑制剂。
CAS:146949-21-5
分子式:C21H17Cl3O3
分子量:423.72
纯度:98%
存储:Store at -20°C

Background:

Pocapavir is an investigational enterovirus (EV) capsid inhibitor.


Pocapavir acts as a capsid inhibitor, preventing virion uncoating upon entry into the cell. Treatment with Pocapavir is safe and significantly accelerates virus clearance[1]. Pocapavir, an investigational oral antiviral, has been used in a case of neonatal enterovirus sepsis. Pocapavir, also known as SCH 48973 and V-073, is a potent, selective anti-enteroviral agent only available as an emergency investigational drug. Pocapavir belongs to a picornavirus antiviral mechanistic class called capsid inhibitors that block virus uncoating and viral RNA release into cells, which in turn prevents virus replication[2].



[1]. Collett MS, et al. Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model. J Infect Dis. 2017 Feb 1;215(3):335-343. [2]. Wittekind SG, et al. Neonatal Enterovirus Myocarditis With Severe Dystrophic Calcification: Novel Treatment WithPocapavir. J Investig Med High Impact Case Rep. 2017 Sep 14;5(3):2324709617729393.