CephalosporinCzincsalt是一种有效的SAMHD1抑制剂,IC50值为1.1μM。
CAS:59143-60-1
分子式:C16H19N3O8SZn
分子量:478.78
纯度:98%
存储:Store at -20°C
Background:
Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 μM.
Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 ± 0.1 μM, 200-fold more potent than Na+ salt form of Cephalosporin C (ICC50CC-Na = 213 ± 30 μM)[1].
[1]. Seamon KJ, et al. A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase. J Biomol Screen. 2015 Jul;20(6):801-9.