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Z-321
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Z-321图片
CAS NO:130849-58-0
规格:98%
分子量:344.47
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Z-321是一个脯氨酰内肽酶(PEP)抑制剂。
CAS:130849-58-0
分子式:C19H24N2O2S
分子量:344.47
纯度:98%
存储:Store at -20°C

Background:

Z-321 is a prolylendopeptidase (PEP) inhibitor.



Z-321 is a prolylendopeptidase (PEP) inhibitor. In the 100 or 200 mg/kg Z-321-treated groups, mean lordosis quotient (LQ) decreases after administration. However, there is no statistical difference among the values before and after. In contrast, the mean LQ in the 300 mg/kg Z-321-treated females is lower than that before injection (P<0.005). Furthermore, when compare to that in the vehicle-treated control group, mean LQ is also significantly lower (p<0.05). The incidence of soliciting behavior decreases after treatment with 300 mg/kg Z-321, when compare to that before treatment, but there is no statistical difference. The present study also demonstrates that 300 mg/kg Z-321 is effective in inhibiting lordosis behavior without disturbance of locomotor activity[1].


[1]. Oosuka I, et al. Decrease of sexual receptivity by prolylendopeptidase inhibitor in female rats. Jpn J Pharmacol. 2000 May;83(1):82-5.