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FPH1(BRD-6125)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FPH1(BRD-6125)图片
CAS NO:708219-39-0
规格:98%
分子量:388.82
包装与价格:
包装价格(元)
10mg电议
25mg电议

产品介绍
Hepatocyte functional proliferation enhancer
CAS:708219-39-0
分子式:C16H15ClF2N2O3S
分子量:388.82
纯度:98%
存储:Store at -20°C

Background:

FPH1 is a small molecule that promotes the functional proliferation of primary hepatocytes [1].


FPH1 belongs to the functional proliferation hits which are screened out by their ability to permit renewable sourcing of functional human hepatocytes. This ability of FPH1 is not dependent on the donors of the hepatocytes. It has been found that FPH1 was active against the primary human hepatocytes from six cell sources of genetically diverse individuals. Besides that, FPH1 can affect the hepatocyte functions with promoting albumin secretion during the differentiation of iPS cells into iHeps. Moreover, treatment of FPH1 also resulted in the increase of CYP3A4 levels and the decrease of AFP secretion [1].


参考文献:
[1] Shan J, Schwartz R E, Ross N T, et al. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nature chemical biology, 2013.