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Vidofludimus
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Vidofludimus图片
CAS NO:717824-30-1
规格:98%
分子量:355.36
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
DHODH inhibitor
CAS:717824-30-1
分子式:C20H18FNO4
分子量:355.36
纯度:98%
存储:Store at -20°C

Background:

Vidofludimus (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 value of 134nmol/L for human DHODH [1].


Vidofludimus (4SC-101, SC12267) has been reported to dose-dependently inhibit DHODH in an in vitro enzyme assay with IC50 values of 0.134μmol/L, 1.29μmol/L, 10.6μmol/L and 12.9μmol/L in human DHODH, rat DHODH, mouse DHODH and human PBMC, respectively [1]. In addition, Vidofludimus has shown the inhibition of proliferation in phytohemagglutinin-induced lymphocytes with an IC50 value of