Specific and competitive histamin H2-receptor antagonist
CAS：93793-83-0
分子式：C19H28N2O4.HCl
分子量：384.9
纯度：98%
存储：Store at -20°C

Background:

Roxatidine Acetate Hydrochloride is a specific and competitive histamin H2 receptor antagonist.Target: Histamin H2 ReceptorRoxatidine Acetate Hydrochloride is a histamine H2-receptor antagonist which, after almost complete oral absorption (greater than 95%), is rapidly converted to its active metabolite, roxatidine, by esterases in the small intestine, plasma and liver. Roxatidine Acetate Hydrochloride is a potent inhibitor of basal and stimulated gastric acid secretion in animals and humans and, like most other H2-receptor antagonists, has no anti-androgenic effects and does not interfere with the hepatic metabolism of other drugs [1, 2].

参考文献:
[1]. Murdoch, D. and D. McTavish, Roxatidine acetate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic potential in peptic ulcer disease and related disorders. Drugs, 1991. 42(2): p. 240-60.
[2]. Pali-Scholl, I. and E. Jensen-Jarolim, Anti-acid medication as a risk factor for food allergy. Allergy, 2011. 66(4): p. 469-77.