Zabofloxacin (DW-224a Free base) 是一种新型氟萘啶酮喹诺酮，具有 7-吡咯烷酮取代基，被认为是临床试验的有效抗菌候选物。Zabofloxacin (DW-224a Free base) 具有抗革兰氏阳性病原体的优良活性，包括金黄色葡萄球菌 (S. aureus)，化脓性链球菌 (S. pyrigenes) 和肺炎链球菌 (S. pneumonia)。Zabofloxacin (DW-224a Free base) 被认为是治疗喹诺酮类易感和喹诺酮类耐药性淋病的替代药物。
CAS：219680-11-2
分子式：C19H20FN5O4
分子量：401.39
纯度：98%
存储：Store at -20°C

Background:

Zabofloxacin (DW-224a Free base) is a novel fluoronaphthyridone quinolone with a 7-pyrrolidone substituent that is considered a potent antibacterial candidate for clinical trials.Zabofloxacin (DW-224a Free base) has excellent activity against gram-positive pathogens including Steptococcus aureus , Streptococcus pyogenes and S.pneumonia.Zabofloxacin (DW-224a Free base) is considered as an alternative candidate for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP)[1].

[1]. Park HS, et al. Antimicrobial Activity of Zabofloxacin against Clinically Isolated Streptococcus pneumoniae. Molecules. 2016 Nov 17;21(11). pii: E1562.