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Glutaric acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glutaric acid图片
CAS NO:110-94-1
包装:1g
规格:98%
市场价:445元
分子量:132.12

产品介绍
Glutaricacid可诱导年轻大鼠大脑的氧化应激。
CAS:110-94-1
分子式:C5H8O4
分子量:132.12
纯度:98%
存储:Store at -20°C

Background:

Glutaric acid induces oxidative stress in brain of young rats.


Glutaric acid (GA) at concentrations of 1 and 2 mM is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM[1].



[1]. de Oliveira Marques F, et al. acid induces oxidative stress in brain of young rats. Brain Res. 2003 Feb 21;964(1):153-8.