Angiotensinogen(1-14),human是肾素底物血管紧张素原的片段,血管紧张素原是所有血管紧张素肽的前体。
CAS:104180-23-6
分子式:C83H122N24O19
分子量:1760.04
纯度:98%
存储:Store at -20°C
Background:
Angiotensinogen (1-14), human is a fragment of the renin substrate angiotensinogen, a precursor for all angiotensin peptides.
Angiotensinogen (AGT) is the only precursor of all angiotensin peptides. Human AGT has 485 amino acids, including a 33 amino-acid signal peptide. The 10 N-terminal amino acids are cleaved by renin to provide angiotensin I (AngI), which is the source for an array of active angiotensin peptides[1].
[1]. Lu H, et al. Structure and functions of angiotensinogen. Hypertens Res. 2016 Jul;39(7):492-500.