NeuropeptideY(13-36),amide,human是神经肽Y受体(neuropeptideYreceptor)激动剂。
CAS：122341-40-6
分子式：C134H207N41O36S
分子量：3000.4
纯度：98%
存储：Store at -20°C

Background:

Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.

Intraventricular injections of the Y2 neuropeptide Y receptor agonist porcine Neuropeptide Y (13-36) (25-3000 pM) produces a dose-dependent increase (up to 14%; ED50=0.3 nM for overall effects and 0.97 nM for the peak effects) in mean arterial blood pressure in the awake, unrestrains male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat[1].

[1]. Aguirre JA, et al. Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci Lett. 1990 Oct 2;118(1):5-8.