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Metixene hydrochloride hydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Metixene hydrochloride hydrate图片
CAS NO:7081-40-5
包装:10mg
规格:98%
市场价:623元
分子量:363.94

产品介绍
Metixenehydrochloridehydrate是一种抗胆碱能、抗帕金森剂,能够有效抑制二苯羟乙酸奎宁酯与毒蕈碱受体(muscarinicreceptor)结合,IC50和Kd值分别为55nM和15nM。
CAS:7081-40-5
分子式:C20H26ClNOS
分子量:363.94
纯度:98%
存储:Store at -20°C

Background:

Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM[1].


Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM[1].



[1]. Syv?lahti EK, et al. Effects of antiparkinsonian drugs on muscarinic receptor binding in rat brain, heart and lung. Pharmacol Toxicol. 1988 Feb;62(2):90-4.