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FHZ
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FHZ图片
CAS NO:1883737-63-0
规格:98%
分子量:478.49
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
FHZ是一个荧光探针。
CAS:1883737-63-0
分子式:C26H26N2O7
分子量:478.49
纯度:98%
存储:Store at -20°C

Background:

FHZ is a fluorescent probe.


After loaded with probe FHZ and treated with HClO and H2O2/EDTA-Fe2+ in order, HeLa cells display the bright fluorescences from both cyan and green channels. FHZ can give out two different fluorescent signals in the presence of both •OH and HClO, suggesting the synchronous discrimination of •OH and HClO by a dual-channel detection model with two exciting wavelengths. Probe FHZ shows very high specificity to the detections of •OH and HClO with the excitations at 410 and 490 nm, respectively. The probe FHZ can efficiently enter the cellular mitochondria and exhibit the differentiable/visual capabilities to the endogenous •OH and HClO by the dual fluorescent responses[1].


Probe FHZ can rapidly be absorbed into the blood circulation system from the zebrafish intestine, and spread out whole zebrafish tissues, and keep its stability in the blood, organs and tissues in the absence of ROS. The probe can keep its stability in biological environments and only selectively react with •OH and HClO species[1].


[1]. Zhang R, et al. Real-Time Discrimination and Versatile Profiling of Spontaneous Reactive Oxygen Species in Living Organisms with a Single Fluorescent Probe. J Am Chem Soc. 2016 Mar 23;138(11):3769-78.