Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing.
CAS：960129-66-2
分子式：C27H36N10O10
分子量：660.6
纯度：98%
存储：Store at -20°C

Background:

Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, which upon reaching a sufficient concentration activates the cell death pathway in a subset of cells. It is sensitive to extreme pH, high temperatures, and other stressful conditions. At 2.5 ng/ml, EDF has been shown to facilitate mazEF-mediated cell death, significantly reducing population size in E. coli cultures.