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CHAPS
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CHAPS图片
CAS NO:75621-03-3
包装:5g
规格:98%
市场价:1258元
分子量:614.88

产品介绍
Zwitterionic detergent for membrane proteins,nondenaturing
CAS:75621-03-3
分子式:C32H58N2O7S
分子量:614.88
纯度:98%
存储:Store at -20°C

Background:

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins. Target: CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons.CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions and is electrically neutral. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. The critical micelle concentration of CHAPS is 6-10mM.


参考文献:
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[2]. Banerjee P, Joo JB, Buse JT, Dawson G. Differential solubilization of lipids along with membrane proteins by different classes of detergents. Chem Phys Lipids. 1995 Aug 1;77(1):65-78.
[3]. Pasquali C, Fialka I, Huber LA. Preparative two-dimensional gel electrophoresis of membrane proteins. Electrophoresis. 1997 Dec;18(14):2573-81.
[4]. Menshikova I, Menshikov E, Filenko N, Lyubchenko YL. Nucleosomes structure and dynamics: effect of CHAPS. Int J Biochem Mol Biol. 2011;2(2):129-137.
[5]. Krofli A, Sarac B, Be ter-Roga M. Thermodynamic characterization of 3-[(3-cholamidopropyl)-dimethylammonium]-1-propanesulfonate (CHAPS) micellization using isothermal titration calorimetry: temperature, salt, and pH dependence. Langmuir. 2012 Jul 17;28(