您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > IDH1 Inhibitor 3
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
IDH1 Inhibitor 3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IDH1 Inhibitor 3图片
CAS NO:2171081-24-4
规格:98%
分子量:591.56
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
IDH1 Inhibitor 3 (compound 6f) 是突变型的 IDH1 的抑制剂,其对IDH1R132H 的 IC50 值为 45 nM。
CAS:2171081-24-4
分子式:C31H25F4N5O3
分子量:591.56
纯度:98%
存储:Store at -20°C

Background:

IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1]. IC50: 45 nM (IDH1R132H)[1].




[1]. Qiangang Zheng, et al. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (2017) 5262-5266.