N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone, a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes.
CAS:257892-31-2
分子式:C17H17N3O3S
分子量:343.4
纯度:98%
存储:Store at -20°C
Background:
N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.