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Sesquicillin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sesquicillin A图片
包装:1mg
规格:98%
市场价:2769元
分子量:470.6

产品介绍
A fungal metabolite
货号:ajcx23468
CAS:51103-58-3
分子式:C29H42O5
分子量:470.6
溶解度:Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Sesquicillin A is a fungal metabolite that has been found inAlbophoma.1It inhibits the growth ofA. salinabrine shrimp (MIC = 6.25 µg/ml). Sesquicillin is cytotoxic to Jurkat cells (IC50= 34 µM). It induces cell cycle arrest at the G1phase and inhibits proliferation of MCF-7 breast cancer cells when used at a concentration of 20 µg/ml.2


1.Uchida, R., Imasato, R., Yamaguchi, Y., et al.New sesquicillins, insecticidal antibiotics produced by Albophoma sp. FKI-1778J. Antibiot. (Tokyo)58(6)397-404(2005) 2.Jeong, H.W., Lee, H.J., Kho, Y.H., et al.Biological effects of G1 phase arrest compound, sesquicillin, in human breast cancer cell linesBioorg. Med. Chem.10(10)3129-3134(2002)