A metabolite of (S)-naproxen
货号:ajcx25332
CAS:52079-10-4
分子式:C13H12O3
分子量：216.2
溶解度:DMSO: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(S)-O-Desmethyl naproxen is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen; It is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.

1.Miners, J.O., Soulter, S., Tukey, R.H., et al.Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxenBiochem. Pharmacol.51(8)1003-1008(1996)