M7594_0037 is a small molecule inhibitor of human peptide deformylase (HsPDF). HsPDF is an important target for anticancer drug discovery. M7594_0037 exhibits potent anticancer activities against HeLa, A549 and MCF-7 cell lines with IC50s of 35.26, 29.63 and 24.63 μM, respectively. References: Gao J, Wang T, Qiu S, Zhu Y, Liang L, Zheng Y. Structure-Based Drug Design of Small Molecule Peptide Deformylase Inhibitors to Treat Cancer. Molecules. 2016 Mar 23;21(4):396. doi: 10.3390/molecules21040396. PubMed PMID: 27023495.
纯度:≥98%
CAS:774551-07-4