Propargyl-PEG4-alcohol 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG4-alcohol 可用于合成一系列 PROTAC 分子。
货号:ajcx29620
CAS:87450-10-0
分子式:C11H20O5
分子量:232.27
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Propargyl-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.