A neuropeptide with diverse biological activities
货号:ajcx22890
CAS:N/A
分子式:C49H68N14O15.XCF3COOH
分子量：1093.2
溶解度:Formic Acid: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Mca-PLGL-Dap(Dnp)-AR-NH₂is a fluorogenic peptide substrate for matrix metalloproteinases (MMPs).¹Upon cleavage by an MMP, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca has excitation and emission maxima of 328 and 420 nm, respectively.

1.Edkins, T.J., Alhadeff, J.A., Kwok, V., et al.Development and validation of novel enzyme activity methods to assess inhibition of matrix metalloproteinases (MMPs) in human serum by antibodies against enzyme therapeuticsJ. Pharm. Biomed. Anal.70408-414(2012)