A derivative of betulin
货号:ajcx24174
CAS:25613-12-1
分子式:C30H49NO2
分子量：455.7
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Betulinic aldehyde oxime is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .¹It is active againstE. aerogenes,E. coli,E. faecalis,P. aeruginosa,S. aureus, andC. albicans, as well asL. donovaniamastigotes, when used at a concentration of 50 µM.^1,2Betulinic aldehyde oxime (50 µM) is cytotoxic to Huh7 hepatocellular carcinoma cells.²

1.Alakurtti, S., BergstrÖm, P., Sacerdoti-Sierra, N., et al.Anti-leishmanial activity of betulin derivativesJ. Antibiot. (Tokyo)63(3)123-126(2010) 2.Haque, S., Nawrot, D.A., Alakurtti, S., et al.Screening and characterisation of antimicrobial properties of semisynthetic betulin derivativesPLoS One9(7)e102696(2014)