IRAK4-IN-4 是一种白介素-1 受体相关激酶 (IRAK4) 抑制剂，IC50 为 2.8 nM。详细信息请参考专利文献 CN107163044A 中的化合物 15。IRAK4-IN-4 还抑制环 GMP-AM 合酶 (cGAS)，IC50 为 2.1 nM。
货号:ajcx15382
CAS:1850276-58-2
分子式:C22H16N2O2
分子量：340.37
溶解度:DMSO: 25 mg/mL (73.45 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

IRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM[1].

[1]. One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A.