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Garcinoic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Garcinoic Acid图片
规格:98%
分子量:426.6
包装与价格:
包装价格(元)
250ug电议
500ug电议
1mg电议

产品介绍
藤黄酸是从藤黄可乐种子中提取的维生素 E 类似物。 Garcinoic acid 对胶质瘤 C6 癌细胞具有显着的抗增殖作用。
货号:ajcx20632
CAS:91893-83-3
分子式:C27H38O4
分子量:426.6
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 30 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Garcinoic acid is a derivative of vitamin E originally isolated from C. grandiflora.1 It inhibits IL-1β-induced microsomal prostaglandin E2 synthase-1 (mPGES-1) activity in A549 cells when used at concentrations of 1 and 10 μM.2 It has higher antioxidant activity relative to (±)-α-tocopherol in a cell-free assay when used at a concentration of 0.15 mM.3


|1. Monache, F.D., Marta, M., Mac-Quhae, M.M., et al. Two new tocotrienoloic acids from the fruits of Clusia grandiflora Splith. Gazz. Chim. Ital. 114(3-4), 135-137 (1984).|2. Alsabil, K., Suor-Cherer, S., Koeberle, A., et al. Semisynthetic and natural garcinoic acid isoforms as new mPGES-1 inhibitors. Planta Med. 82(11-12), 1110-1116 (2016).|3. Terashima, K., Takaya, Y., and Niwa, M. Powerful antioxidative agents based on garcinoic acid from Garcinia kola. Bioorg. Med. Chem. 10(5), 1619-1625 (2002).