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(R)-(-)-Linoleyl-2'-Hydroxy-1'-Propylamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(R)-(-)-Linoleyl-2'-Hydroxy-1'-Propylamide图片
规格:98%
分子量:337.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group.
货号:ajcx17736
CAS:N/A
分子式:C21H39NO2
分子量:337.5
溶解度:DMF: 11 mg/ml,DMSO: 5 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 11 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Linoleoyl ethanolamide (LOEA) has potential signaling roles in aging and neurological functioning. LOEA has a weak affinity for cannabinoid (CB) receptors (Ki = 10, 25 μM for CB1, CB2, respectively) and inhibits voltage-gated K+ channels. LOEA also inhibits fatty acid amide hydrolase (FAAH; Ki = 9 μM) and is hydrolyzed by FAAH. (R)-(-)-Linoleyl-2'-hydroxy-1'-propylamide is a homolog of LOEA which is characterized by the addition of an (R)-β-methyl group at the terminal ethanolamine carbon. A similar modification of arachidonoyl ethanolamide to produce R-2 methanandamide imparts diminished affinity for the CB receptor as well as reduced metabolic stability. The physiological actions of this compound have not been evaluated.