Aluminum Hydroxide 是铝佐剂的一种主要形式。基于 Aluminum Hydroxide 辅助的研究包括储存库效应、促吞噬作用和激活促炎症的 NLRP3 通路。Aluminum Hydroxide 还作为佐剂补偿亚单位疫苗的低固有免疫原性。
货号:ajcx14678
CAS:21645-51-2
分子式:AlH3O3
分子量：78
溶解度:DMSO:< 1 mg/mL (insoluble or slightly soluble)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Aluminum Hydroxide is a main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches including the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines[1][2].

[1]. He P, et al. Advances in aluminum hydroxide-based adjuvant research and its mechanism. Hum Vaccin Immunother. 2015;11(2):477-88. [2]. Amini Y, et al. Aluminum hydroxide nanoparticles show strong activity to stimulate Th-1 immune response against tuberculosis. Artif Cells Nanomed Biotechnol. 2017 Nov;45(7):1331-1335.