A neuropeptide with diverse biological activities
货号:ajcx23336
CAS:N/A
分子式:C22H33D4NO5
分子量:399.6
溶解度:DMF: >100mg/ml,DMSO: >100mg/ml,Ethanol: >100mg/ml,PBS (pH 7.2): 12 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Prostaglandin E2ethanolamide (PGE2-EA)-d4contains four deuterium atoms. It is intended for use as an internal standard for the quantification of PGE2-EA by GC-or LC-mass spectrometry. PGE2-EA is an analog of PGE2with improved water solubility and stability. PGE2-EA acts as an agonist with all four known EP receptor subtypes, but with an affinity that is significantly reduced compared to PGE2.1PGE2-EA is produced by HCA-7 cells treated with arachidonoyl ethanolamide.2
1.Ross, R.A., Craib, S.J., Stevenson, L.A., et al.Pharmacological characterization of the anandamide cyclooxygenase metabolite: Prostaglandin E2 ethanolamideJ. Pharmacol. Exp. Ther.301(3)900-907(2002)
2.Kozak, K.R., Crews, B.C., Morrow, J.D., et al.Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamidesJ. Biol. Chem.277(47)44877-44885(2002)