An active metabolite of hydroxychloroquine
货号:ajcx22236
CAS:4298-15-1
分子式:C16H22ClN3O
分子量：307.8
溶解度:DMF: soluble,DMSO: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .¹It is formedviathe desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.

1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018)