A neuropeptide with diverse biological activities
货号:ajcx20650
CAS:N/A
分子式:C49H80N14O18 • XCF3COOH
分子量：1153.3
溶解度:Water: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Histone H2AX (134-143) is a C-terminal peptide fragment of histone H2AX that corresponds to amino acid residues 134-143 of the human histone H2AX sequence. Histone H2AX (134-143) is an evolutionarily conserved motif that differentiates histone H2AX from other H2A histones.1 It contains a serine residue that is rapidly phosphorylated upon introduction of DNA double-strand breaks and initiation of DNA fragmentation during apoptosis.

|1. Rogakou, E.P., Nieves-Neira, W., Boon, C., et al. Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139. J. Biol. Chem. 275(13), 9390-9395 (2000).