The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids.
货号:ajcx18940
CAS:N/A
分子式:C41H78O19P3 •3Na
分子量：1036.9
溶解度:Chloroform: .1 mg/ml,Chloroform:Methanol:Water: 1 mg/ml,Water: 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns PtdIns-(4,5)-P2 (1,2-dipalmitoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) containing C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. The natural compound is the product of PtdIns-4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.