A tropane alkaloid and an active metabolite of scopolamine
货号:ajcx26604
CAS:535-26-2
分子式:C17H19NO3
分子量：285.3
溶解度:DMSO: slightly soluble w/ heat,Methanol: slightly soluble w/ sonication
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Aposcopolamine is a tropane alkaloid that has been found inD. feroxand is an active metabolite of the muscarinic antagonist scopolamine.^1,2It is selective for muscarinic acetylcholine receptors (mAChRs) over nicotinic AChRs (nAChRs; IC₅₀s = 0.0192 and 188 µM, respectively).³

1.Vitale, A.A., Acher , A., and Pomilio, A.B.Alkaloids of Datura ferox from ArgentinaJ. Ethnaopharmacol.49(2)81-89(1995) 2.Chen, H., Chen, Y., Du, P., et al.Liquid chromatography-electrospray ionization ion trap mass spectrometry for analysis of in vivo and in vitro metabolites of scopolamine in ratsJ. Chromatogr. Sci.46(1)74-80(2008) 3.Schmeller, T., Sporer, F., Sauerwein, M., et al.Binding of tropane alkaloids to nicotinic and muscarinic acetylcholine receptorsPharmazie50(7)493-495(1995)