C42H65N13O10•XCF3COOH
货号:ajcx23876
CAS:N/A
分子式:C42H65N13O10•XCF3COOH
分子量：912.1
溶解度:DMSO: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Saralasin is a peptide angiotensin II type 2 (AT₂) receptor agonist.¹It binds to AT₂receptors (K_i= 0.38 nM) and induces neurite outgrowth in NG108-15 cells when used at a concentration at 100 nM, an effect that can be inhibited by the AT₂receptor antagonist PD 123310. Saralasin (5 µg/animal, i.c.v.) enhances acquisition of the conditioned avoidance response in rats.²

1.Guimond, M.-O., Hallberg, M., Gallo-Payet, N., et al.Saralasin and sarile are AT2 receptor agonistsACS Med. Chem. Lett.5(10)1129-1132(2014) 2.Wright, J.W., and Harding, J.W.Brain angiotensin receptor subtypes AT1, AT2, and AT4 and their functionsRegul. Pept.59(3)269-295(1995)