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Met-Enkephalin(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Met-Enkephalin(trifluoroacetate salt)图片
包装:5mg
规格:98%
市场价:733元
分子量:573.7

产品介绍
Met-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ- and μ-opioid receptors (Kis = 0.65 and 1.7 nM, respectively).
货号:ajcx18662
CAS:N/A
分子式:C27H35N5O7S•XCF3COOH
分子量:573.7
溶解度:Water: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Met-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ- and µ-opioid receptors (Kis = 0.65 and 1.7 nM, respectively). It is selective for δ- and µ- over κ-opioid receptors (Ki = >1,000 nM). Met-Enkephalin is a cleavage product of proenkephalin, which is found primarily in the adrenal medulla and the CNS. Met-Enkephalin is found in the brain, primarily in the globus pallidus, nucleus accumbens, and substantia nigra, the brainstem, and the spinal cord as well as in the peripheral nervous system. Met-Enkephalin has antinociceptive effects in mouse models of acute pain, including tail pressure, hot plate tail-flick, and acetic acid-induced writhing tests (ED50s = 170, 140, and 88 nmol/animal, respectively). Levels of Met-enkephalin are increased at the site of inflammation in a complete Freund's adjuvant mouse model of chronic inflammatory pain.