包装: | 1mg |
规格: | 98% |
市场价: | 4047元 |
分子量: | 305.3 |
Background:
rac-Hesperetin-d3is intended for use as an internal standard for the quantification of hesperetin by GC- or LC-MS.rac-Hesperetin is a racemic mixture of the flavanones (S)-hesperetin and (R)-hesperetin.rac-Hesperetin (1 mM) inhibits heat-induced advanced glycation end product formation between BSA and glucose by 56.7%.1It also inhibits α-glucosidase and protein tyrosine phosphatase 1B (PTP1B; IC50s = 15.28 and 20.16 µM, respectively).2rac-Hesperetin (100 µM) protects against hydrogen peroxide-induced cytotoxicity in MIN6 pancreatic beta cells by 72.27%.
1.Li, D., Mitsuhashi, S., and Ubukata, M.Protective effects of hesperidin derivatives and their stereoisomers against advanced glycation end-products formationPharm. Biol.50(12)1531-1535(2012) 2.Xu, J., Wang, X., Yue, J., et al.Polyphenols from acorn leaves (Quercus liaotungensis) protect pancreatic beta cells and their inhibitory activity against α-glucosidase and protein tyrosine phosphatase 1BMolecules23(9)2167(2018)