羟基去甲基波生坦 (Ro 64-105) 是由肝脏中的细胞色素 P450 酶 CYP2C9 和 CYP3A4 产生的波生坦代谢。
货号:ajcx25326
CAS:253688-62-9
分子式:C26H27N5O7S
分子量：553.6
溶解度:DMSO: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Hydroxy desmethyl bosentan is a metabolite of the endothelin receptor antagonist bosentan .¹

1.van Giersbergen, P.L.M., Gnerre, C., Treiber, A., et al.Bosentan, a dual endothelin receptor antagonist, activates the pregnane X nuclear receptorBr. J. Clin. Pharmacol.54(5)561-562(2002)