A metabolite of riluzole
货号:ajcx25244
CAS:179070-90-7
分子式:C8H5F3N2O2S
分子量：250.2
溶解度:Acetonitrile: soluble,DMSO: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

N-hydroxy Riluzole is a metabolite of the antiglutamatergic agent riluzole .¹It is formed from riluzole predominantly by the cytochrome P450 (CYP) isoform CYP1A2 in human hepatic microsomes.

1.Sanderink, G.J., Bournique, B., Stevens, J., et al.Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitroJ. Pharmacol. Exp. Ther.282(3)1465-1472(1997)