Halazone 是一种非典型的抗菌磺酰胺衍生物，是碳酸酐酶 II (carbonic anhydrase II) 抑制剂，Kd 值为 1.45 µM。Halazone 可保护钠通道免于灭活。Halazone 被广泛用于饮用水消毒。
货号:ajcx17310
CAS:80-13-7
分子式:C7H5Cl2NO4S
分子量：270.09
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2].

[1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64. [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91.