Thalidomide-O-amido-C3-NH2 TFA 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。
货号:ajcx14308
CAS:2022182-58-5
分子式:C20H21F3N4O8
分子量：502.4
溶解度:DMSO: 125 mg/mL (248.81 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

[1]. Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.