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XLR11 N-(4-hydroxypentyl)metabolite-d5(CRM)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
XLR11 N-(4-hydroxypentyl)metabolite-d5(CRM)图片
包装:100ug
规格:98%
市场价:973元
分子量:350.5

产品介绍
C21H23D5FNO2
货号:ajcx24472
CAS:N/A
分子式:C21H23D5FNO2
分子量:350.5
溶解度:
纯度:98%
存储:Store at -20°C
库存:现货

Background:

XLR11 N-(4-hydroxypentyl) metabolite-d5(CRM) is intended for use as an internal standard for the quantification of XLR11 N-(4-hydroxypentyl) metabolite by GC-or LC-mass spectrometry. XLR11 is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2receptor over the central CB1receptor.1XLR11 also has an N-(5-fluoropentyl) chain, which increases binding to both CB receptors.2XLR11 N-(4-hydroxypentyl) metabolite is an expected phase 1 metabolite of XLR11, based on the known metabolism of similar compounds.3,4The physiological properties of this compound have not been evaluated. This product is intended for forensic and research applications.


1.Frost, J.M., Dart, M.J., Tietje, K.R., et al.Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activityJ. Med. Chem.53(1)295-315(2010) 2.Makriyannis, A., and Deng, H.Cannabimimetic indole derivativesPCT/US00/28832(2001) 3.Zhang, Q., Ma, P., Cole, R.B., et al.Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MSAnalytical and Bioanalytical Chemistry3861345-1355(2006) 4.Wintermeyer, A., MÖller, I., Thevis, M., et al.In vitro phase I metabolism of the synthetic cannabimimetic JWH-018Anal. Bioanal. Chem.398(5)2141-2153(2010)