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Palmitoyl Ethanolamide-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Palmitoyl Ethanolamide-d4图片
规格:98%
分子量:303.5
包装与价格:
包装价格(元)
100ug电议
500ug电议
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of palmitoyl ethanolamide
货号:ajcx23222
CAS:946524-34-1
分子式:C18H33D4NO2
分子量:303.5
溶解度:DMF: 10 mg/ml,DMSO: 5 mg/ml,Ethanol: 2 mg/ml,Ethanol:PBS (pH 7.2) (1:10): .01 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Palmitoyl ethanolamide-d4(PEA-d4) contains four deuterium atoms at the 1,1', 2, and 2' positions. It is intended for use as an internal standard for the quantification of PEA by GC-or LC-mass spectrometry. Palmitoyl ethanolamide (PEA) is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.1PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activityin vitro.2PEA is an endocannabinoid which has been shown to significantly elevate cAMP in cells expressing CB2receptors. However, its affinity for CB2receptors is relatively low, at about 10 µM. CB1receptors have no appreciable affinity for PEA.3


1.Bachur, N.R., Masek, K., Melmon, K.L., et al.Fatty acid amides of ethanolamine in mammalian tissuesJ. Biol. Chem.2401019-1024(1965) 2.Ganley, O.H., Graessle, O.E., Robinson, H.J., et al.Anti-inflammatory activity of compounds obtained from egg yolk, peanut oil, and soybean lecithinJournal of Laboratory and Clinical Medicine51709-714(1958) 3.Devane, W.A., Hanus, L., Breuer, A., et al.Isolation and structure of a brain constituent that binds to the cannabinoid receptorScience258(5090)1946-1949(1992)