A fungicide that inhibits the sterol pathway
货号:ajcx22486
CAS:67564-91-4
分子式:C20H33NO
分子量：303.5
溶解度:DMF: 15 mg/ml,DMSO: 5 mg/ml,Ethanol: 15 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Fenpropimorph is a fungicide that inhibits the sterol pathway.¹It inhibits δ⁸-δ⁷-sterol isomerase in yeast at low concentrations, with δ¹⁴-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol .²Fenpropimorph is also able to inhibit sterol synthesis in certain plants and mammalian cells.^1,3

1.Costet, M.F., Achouri, M.E., Charlet, M., et al.Ecdysteroid biosynthesis and embryonic development are disturbed in insects (Locusta migratoria) reared on plant diet (Triticum sativum) with a selectively modified sterol profileProc. Natl. Acad. Sci. USA84(3)643-647(1987) 2.Marcireau, C., Guilloton, M., and Karst, F.In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal propertyAntimicrob. Agents Chemother.34(6)989-993(1990) 3.Corio-Costet, M.F., Gerst, N., Benveniste, P., et al.Inhibition by the fungicide fenpropimorph of cholesterol biosynthesis in 3T3 fibroblastsBiochem J.256(3)829-834(1988)